I've seen this when multiple agents are installed in parallel on one machine.  The first agent gets "kworking" and the next agent gets "kworking1" and soforth...

How do I tell if there's 2 agents on the machine and then remove one of them? Is there a master kaseya .ini file somewhere that could be resetting the Working Directory?

Usually it will show 2 agents in Add/Remove Programs

I checked and there was only one instance of Kaseya in Add/Remove Programs. I've gotten some to stay changed by changing in Agent> Working Directory and Live Connect> Agent Settings> Working Directory at the same time, but some changed back after a short time period. I just changed 1 that had turned back and also edited the C:\Program Files\Kaseya\Agent\KaseyaD.ini file reference. Will see it that holds...

Check services.msc and/or program files directories for agents.  We hide our agent from add/remove programs.  Even task manager to see if multiples are running

One note of interest. The two groups that we are having this issue with are both running Trend Micro Worry-Free Business Anti-Virus. Any other Trend users having this issue?

I have seen this too. In my case I was able to fix the issue by deleting the C:\CompanyName directory and then changing the Working Directory to C:\CompanyName. The agent will recreate the directory and begin using it.

Thanks, I will give that a try!

   I deleted the working directories and changed (reset) them back to c:\companyname but when my daily scripts ran and it checks the Trend Micro Defs Age, they went back to c:\companyname1. Both companies just renewed their Trend Micro AV licenses and the issues appear to have started since then. I'm excluding c:\program files\kaseya and c:\companyname in Trend WFB.

  What program does K2 use at the client for executing scripts?